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验证数据展示

  • WB analysis using 68473-1-Ig (same clone as 68473-1-PBS)

    WB analysis using 68473-1-Ig (same clone as 68473-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68473-1-Ig (MEN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

    IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

    IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50886-1

    Cytometric bead array standard curve of MP50886-1

    Cytometric bead array standard curve of MP50886-1, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-2-PBS. Detection antibody: 68473-1-PBS. Standard:Ag7566. Range: 1.563-200 ng/mL.

  • Cytometric bead array standard curve of MP50886-2

    Cytometric bead array standard curve of MP50886-2

    Cytometric bead array standard curve of MP50886-2, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-1-PBS. Detection antibody: 68473-3-PBS. Standard:Ag7566. Range: 3.125-200 ng/mL.

MEN1 Monoclonal antibody, PBS Only (Capture/Detector)

MEN1 Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Cat No. 68473-1-PBS

产品说明书

CloneNo. 3A6A11

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Cytometric bead array, Indirect ELISA

别名

SCG2, Menin 1, Menin, MEAI, 3A6A11

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68473-1-PBS targets MEN1 as part of a matched antibody pair:

MP50886-1: 68473-2-PBS capture and 68473-1-PBS detection (validated in Cytometric bead array)

MP50886-2: 68473-1-PBS capture and 68473-3-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IHC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 MEN1 fusion protein Ag7566 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 multiple endocrine neoplasia I
别名 SCG2, Menin 1, Menin, MEAI, 3A6A11
计算分子量 68 kDa
观测分子量68-70 kDa
GenBank蛋白编号BC002544
基因名称 MEN1
Gene ID (NCBI) 4221
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO00255
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MEN1, also named as Menin or MEAI, is a tumor suppressor protein encoded by the MEN1 gene. It is located in nucleus and ubiquitous expression in spleen and lymph node. The calculated molecular weight of MEN1 is 68 kDa. Its inactivation has been implicated in tumors of many endocrine tissues. Germline inactivating mutations of MEN1 gene are the main cause of multiple endocrine neoplasia type 1 (MEN1), a syndrome characterized by tumors in the pituitary gland, the parathyroid glands, and the enteropancreatic neuroendocrine tissues. Recent study shows astroglia menin deficiency leads to depressive-like behaviors in mice.