验证数据展示
产品信息
17652-1-PBS targets MED27 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag11897 Product name: Recombinant human MED27 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-311 aa of BC064608 Sequence: MADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | mediator complex subunit 27 |
| 别名 | Cofactor required for Sp1 transcriptional activation subunit 8, CRAP34, CRSP34, CRSP8, MED 27 |
| 计算分子量 | 311 aa, 35 kDa |
| 观测分子量 | 34 kDa |
| GenBank蛋白编号 | BC064608 |
| 基因名称 | MED27 |
| Gene ID (NCBI) | 9442 |
| RRID | AB_3741928 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6P2C8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MED27 is a subunit of the Mediator complex, a large multiprotein complex that acts as a bridge between DNA-binding transcription factors and the RNA polymerase II transcriptional machinery. It is involved in the regulation of gene transcription and is essential for the initiation of transcription. The protein is highly conserved across different species, highlighting its fundamental role in cellular processes. It also influences cellular growth, development, and response to environmental cues.
