验证数据展示
经过测试的应用
Positive WB detected in | rat kidney tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:1000-1:6000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
85339-1-RR targets MCOLN1 in WB, ELISA applications and shows reactivity with human, rat samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | human, rat |
免疫原 | MCOLN1 fusion protein Ag7493 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | mucolipin 1 |
别名 | MST080, MLIV, ML4, ML1, MG 2 |
计算分子量 | 65 kDa |
观测分子量 | 60 kDa |
GenBank蛋白编号 | BC005149 |
基因名称 | MCOLN1 |
Gene ID (NCBI) | 57192 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9GZU1 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.
实验方案
Product Specific Protocols | |
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WB protocol for MCOLN1 antibody 85339-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |