验证数据展示
产品信息
85339-1-PBS targets MCOLN1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, rat |
免疫原 | MCOLN1 fusion protein Ag7493 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | mucolipin 1 |
别名 | MST080, MLIV, ML4, ML1, MG 2 |
计算分子量 | 65 kDa |
观测分子量 | 60 kDa |
GenBank蛋白编号 | BC005149 |
基因名称 | MCOLN1 |
Gene ID (NCBI) | 57192 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9GZU1 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.