• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

    WB analysis of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

    rat kidney tissue were subjected to SDS PAGE followed by western blot with 85339-1-RR (MCOLN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

    IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

    IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

    IHC staining of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

    {{ptg:ProductFeaturesInfo}}

MCOLN1 Recombinant monoclonal antibody, PBS Only

MCOLN1 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 85339-1-PBS

产品说明书

CloneNo. 242586D4

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, IHC, Indirect ELISA

别名

242586D4, MG 2, ML1, ML4, MLIV

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

85339-1-PBS targets MCOLN1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原

CatNo: Ag7493

Product name: Recombinant human MCOLN1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 90-299 aa of BC005149

Sequence: AVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 mucolipin 1
别名 242586D4, MG 2, ML1, ML4, MLIV
计算分子量 65 kDa
观测分子量60 kDa
GenBank蛋白编号BC005149
基因名称 MCOLN1
Gene ID (NCBI) 57192
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9GZU1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.