×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 15291-1-AP (same clone as 15291-1-PBS)

    WB analysis using 15291-1-AP (same clone as 15291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15291-1-AP (MCOLN1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 15291-1-AP (same clone as 15291-1-PBS)

    IHC staining of mouse brain using 15291-1-AP (same clone as 15291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15291-1-AP (MCOLN1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 15291-1-AP (same clone as 15291-1-PBS)

    IF Staining of U2OS using 15291-1-AP (same clone as 15291-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using MCOLN1 antibody (15291-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

MCOLN1 Polyclonal antibody, PBS Only

MCOLN1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 15291-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

MG 2, ML1, ML4, MLIV, MST080

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

15291-1-PBS targets MCOLN1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag7493

Product name: Recombinant human MCOLN1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 90-299 aa of BC005149

Sequence: AVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 mucolipin 1
别名 MG 2, ML1, ML4, MLIV, MST080
计算分子量 65 kDa
观测分子量60-65 kDa
GenBank蛋白编号BC005149
基因名称 MCOLN1
Gene ID (NCBI) 57192
RRIDAB_2935438
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9GZU1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.

||
New chat

Able™

正在加载，请稍候...