MCOLN1 Polyclonal antibody
MCOLN1 Polyclonal Antibody for IF/ICC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF/ICC, WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | human placenta tissue, mouse kidney tissue, rat kidney tissue |
Positive IF detected in | U2OS cells |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
Immunofluorescence (IF) | IF : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
15291-1-AP targets MCOLN1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | IF/ICC, WB, ELISA |
Tested Reactivity | human, mouse, rat |
Cited Reactivity | human |
Immunogen | MCOLN1 fusion protein Ag7493 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | mucolipin 1 |
Synonyms | MCOLN1, MG 2, ML4, MLIV, MST080, MSTP080, Mucolipidin, mucolipin 1, TRP ML1, TRPM L1, TRPML1 |
Calculated Molecular Weight | 65 kDa |
Observed Molecular Weight | 60-65 kDa |
GenBank Accession Number | BC005149 |
Gene Symbol | MCOLN1 |
Gene ID (NCBI) | 57192 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9GZU1 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.
实验方案
Product Specific Protocols | |
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WB protocol for MCOLN1 antibody 15291-1-AP | Download protocol |
IF protocol for MCOLN1 antibody 15291-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Autophagy Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy |