验证数据展示
经过测试的应用
Positive FC detected in | mouse bone marrow cells |
推荐稀释比
应用 | 推荐稀释比 |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-65296 targets Ly-6C in FC applications and shows reactivity with Mouse samples.
经测试应用 | FC Application Description |
经测试反应性 | Mouse |
免疫原 | L3 cloned CTL cells 种属同源性预测 |
宿主/亚型 | Rat / IgG2c |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | lymphocyte antigen 6 complex, locus C1 |
别名 | AA682074, AA959465, Ly 6C, Ly6c, Ly6c1 |
GenBank蛋白编号 | BC010764 |
基因名称 | Ly-6C |
Gene ID (NCBI) | 17067 |
RRID | AB_3672875 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Affinity purification |
储存缓冲液 | PBS with 0.09% sodium azide , pH 7.3 |
储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Ly-6C (lymphocyte antigen 6 complex, locus C) is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of glycosyl phosphatidylinositol-anchored surface glycoproteins (PMID: 9192663). Ly-6C is expressed on mouse monocytes/macrophages, endothelial cells, granulocytes, thymocytes, and some T cell subsets (PMID: 2849552). The two alleles of Ly-6C, Ly-6C.1 and Ly-6C.2, result in differential expression of this protein on subpopulations of CD4+ T cells (PMID: 15057973; 9126982). Ly-6C has been reported as a marker of memory CD8+ T cells (PMID: 7543536).
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 488 Ly-6C antibody CL488-65296 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |