• Featured Product
  • KD/KO验证

LTBP1 Polyclonal antibody

LTBP1 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 26855-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

WB, IHC, IF/ICC, ELISA and More (1)

LTBP 1, LTBP1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman plasma tissue
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inHeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26855-1-AP targets LTBP1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human
文献引用反应性human, mouse
免疫原 LTBP1 fusion protein Ag25392 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 latent transforming growth factor beta binding protein 1
别名 LTBP 1, LTBP1
计算分子量 1721 aa, 187 kDa
观测分子量 150 kDa
GenBank蛋白编号BC130289
基因名称 LTBP1
Gene ID (NCBI) 4052
RRIDAB_2880658
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14766
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Latent TGFβ binding protein 1 (LTBP1) is a large extracellular protein which belongs to the family of latent TGF-beta binding proteins (LTBPs). LTBP1 is essential for TGF-beta folding, secretion, matrix localization and activation. LTBP1 has also been demonstrated to interact with a number of insoluble extracellular matrix components, such as fibrillin. We got 150-240 kDa in western blotting due to protein glycosylation of LTBP1 (PMID: 18086923, PMID: 9923648 ).

实验方案

Product Specific Protocols
WB protocol for LTBP1 antibody 26855-1-APDownload protocol
IHC protocol for LTBP1 antibody 26855-1-APDownload protocol
IF protocol for LTBP1 antibody 26855-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIF

Cell Rep

Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis

Authors - Jose Verdezoto Mosquera
humanWB,IHC

J Transl Med

LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.

Authors - Rui Cai
  • KD Validated
humanWB

Cell Death Discov

ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.

Authors - Mingqing Cui
human,mouseIHC

medRxiv

Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations

Authors - Rédouane Aherrahrou
humanWB,IF

Adv Mater

Engineered Surfaces that Promote Capture of Latent Proteins to Facilitate Integrin-Mediated Mechanical Activation of Growth Factors

Authors - Udesh Dhawan
humanWB

Front Immunol

Hypoxia reconstructed colorectal tumor microenvironment weakening anti-tumor immunity: construction of a new prognosis predicting model through transcriptome analysis

Authors - Ruizhi Zhang
Loading...