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验证数据展示

  • WB analysis using 28057-1-AP (same clone as 28057-1-PBS)

    WB analysis using 28057-1-AP (same clone as 28057-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28057-1-AP (LRRC2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28057-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 28057-1-AP (same clone as 28057-1-PBS)

    IHC staining of mouse skeletal muscle using 28057-1-AP (same clone as 28057-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 28057-1-AP (LRRC2 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28057-1-PBS in a different storage buffer formulation.

LRRC2 Polyclonal antibody, PBS Only

LRRC2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28057-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

28057-1-PBS targets LRRC2 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 mouse, rat
免疫原

CatNo: Ag27830

Product name: Recombinant human LRRC2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 18-200 aa of BC029118

Sequence: ETRVKKHKAWQKKEVERLEKSALEKIKEEWNFVAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 leucine rich repeat containing 2
别名
计算分子量 371 aa, 43 kDa
观测分子量38 kDa
GenBank蛋白编号BC029118
基因名称 LRRC2
Gene ID (NCBI) 79442
RRIDAB_3669639
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BYS8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Leucine Rich Repeat Containing 2 (LRRC2) was found to be localized to the mitochondria in human cells and transcriptionally regulated by the mitochondrial master regulator Pgc-1α. It has been reported that Lrrc2 transcript abundance correlates with that of β-MHC, a canonical marker of cardiac hypertrophy in humans, and experimentally demonstrated an elevation in Lrrc2 transcript in vitro and in vivo rodent models of cardiac hypertrophy as well as in patients with dilated cardiomyopathy. (PMID: 28158196)

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