验证数据展示
产品信息
18821-1-PBS targets LILRA5/CD85f in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| 别名 | LILRA5, CD85, CD85 antigen-like family member F, CD85f, ILT 11 |
| 计算分子量 | 299 aa, 33 kDa |
| 观测分子量 | 31-33 kDa |
| GenBank蛋白编号 | BC153203 |
| 基因名称 | LILRA5 |
| Gene ID (NCBI) | 353514 |
| RRID | AB_2281279 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | A6NI73 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LILRA5, also named as CD85f, ILT11, LILRB7 or LIR9, is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is a group of immune inhibitory and stimulatory receptors (PMID: 15304001). There are two membrane-bound and two soluble forms of LILRA5. The transmembrane LILRA5 contains a short cytoplasmic domain and a charged arginine residue within the transmembrane region (PMID: 19009525). It is mostly expressed in myeloid cells, including monocytes and neutrophils (PMID: 12393390). LILRA5 may play a role in triggering innate immune responses. It does not function in class I MHC antigens recognition (PMID: 16675463). The antibody recognizes the isoform 1 and isoform 2 of LILRA5.
