验证数据展示
经过测试的应用
| Positive WB detected in | HT-1080 cells, HeLa cells, HEK-293 cells, Jurkat cells, SGC-7901 cells |
Planning an IHC experiment? We recommend our IHCeasy LATS2 Ready-To-Use IHC Kit. LATS2 primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
88282-1-RR targets LATS2-Specific in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | LATS, large tumor suppressor, homolog 2 (Drosophila) |
| 别名 | LATS2, EC:2.7.11.1, KPM, LATS 2, Serine/threonine-protein kinase kpm |
| 计算分子量 | 120 kDa |
| 观测分子量 | 130-150 kDa |
| GenBank蛋白编号 | NM_014572 |
| 基因名称 | LATS2 |
| Gene ID (NCBI) | 26524 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NRM7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LATS2, also named as KPM, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. LATS2 is a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. It is a negative regulator of the androgen receptor. LATS2 has a calculated molecular mass of 120 kDa and an apparent molecular mass of 150 kDa (PMID: 10871863). The antibody is specific to LATS2.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for LATS2-Specific antibody 88282-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
