验证数据展示
Planning an IHC experiment? We recommend our IHCeasy LATS2 Ready-To-Use IHC Kit. LATS2 primary antibody included.
产品信息
88282-1-PBS targets LATS2-Specific in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | LATS, large tumor suppressor, homolog 2 (Drosophila) |
| 别名 | LATS2, EC:2.7.11.1, KPM, LATS 2, Serine/threonine-protein kinase kpm |
| 计算分子量 | 120 kDa |
| 观测分子量 | 130-150 kDa |
| GenBank蛋白编号 | NM_014572 |
| 基因名称 | LATS2 |
| Gene ID (NCBI) | 26524 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NRM7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LATS2, also named as KPM, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. LATS2 is a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. It is a negative regulator of the androgen receptor. LATS2 has a calculated molecular mass of 120 kDa and an apparent molecular mass of 150 kDa (PMID: 10871863). The antibody is specific to LATS2.
