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KLHL11 Polyclonal antibody

KLHL11 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 17117-1-AP

Print datasheet

Synonyms

kelch like 11 (Drosophila), Kelch like protein 11, KLHL11

验证数据展示

  • WB analysis of COLO 320 using 17117-1-AP

    WB analysis of COLO 320 using 17117-1-AP

    COLO 320 cells were subjected to SDS PAGE followed by western blot with 17117-1-AP (KLHL11 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inCOLO 320 cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17117-1-AP targets KLHL11 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen KLHL11 fusion protein Ag10805 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name kelch-like 11 (Drosophila)
Synonyms kelch like 11 (Drosophila), Kelch like protein 11, KLHL11
Calculated Molecular Weight 708 aa, 80 kDa
Observed Molecular Weight 80 kDa
GenBank Accession NumberBC034470
Gene Symbol KLHL11
Gene ID (NCBI) 55175
RRIDAB_2130733
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NVR0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KLHL11 is a component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating ubiquitination of target proteins. The presence of antibodies directed against KLHL11 has been identified as biomarker of a paraneoplastic neurological syndrome. The downregulation of KLHL11 may contribute to the disease progression, owing to its putative function in protein quality control. The calculated molecular weight of KLHL11 is 80 kDa (PMID: 34312900).

实验方案

Product Specific Protocols
WB protocol for KLHL11 antibody 17117-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols