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验证数据展示

  • IHC staining of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    IHC staining of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21186-1-AP (KIF5A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21186-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    IHC staining of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21186-1-AP (KIF5A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21186-1-PBS in a different storage buffer formulation.

  • WB analysis using 21186-1-AP (same clone as 21186-1-PBS)

    WB analysis using 21186-1-AP (same clone as 21186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21186-1-AP (KIF5A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21186-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    IP experiment of mouse brain using 21186-1-AP (same clone as 21186-1-PBS)

    IP result of anti-KIF5A (IP:21186-1-AP, 4ug; Detection:21186-1-AP 1:2000) with mouse brain tissue lysate 1840 ug. This data was developed using the same antibody clone with 21186-1-PBS in a different storage buffer formulation.

  • IF Staining of PC-12 using 21186-1-AP (same clone as 21186-1-PBS)

    IF Staining of PC-12 using 21186-1-AP (same clone as 21186-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PC-12 cells using KIF5A antibody (21186-1-AP) at dilution of 1:200 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 21186-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

KIF5A Polyclonal antibody, PBS Only

KIF5A Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 21186-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

NKHC, Neuronal kinesin heavy chain, MY050, Kinesin heavy chain neuron-specific 1, Kinesin heavy chain isoform 5A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

21186-1-PBS targets KIF5A in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 KIF5A fusion protein Ag15518 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 kinesin family member 5A
别名 NKHC, Neuronal kinesin heavy chain, MY050, Kinesin heavy chain neuron-specific 1, Kinesin heavy chain isoform 5A
计算分子量 1032 aa, 117 kDa
观测分子量 118-120 kDa
GenBank蛋白编号BC146670
基因名称 KIF5A
Gene ID (NCBI) 3798
RRIDAB_10733125
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ12840
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Kinesin superfamily proteins (KIFs) are microtubule-based molecular motors essential for the intracellular transport of various cargos, including organelles, proteins, and RNAs. KIF5A is expressed exclusively in neurons and transports neuronal cargoes into axons and dendrites. KIF5A mutations have been associated with Charcot-Marie-Tooth Type 2, an axonal peripheral neuropathy characterized by progressive loss of peripheral sensation and muscle wasting.