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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP result of anti-KHSRP (IP:82931-2-RR, 4ug; Detection:82931-2-RR 1:2500) with HeLa cells lysate 1050 ug. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    1x10^6 U-251 cells were intracellularly stained with 0.25 ug Anti-Human KHSRP (82931-2-RR, Clone:230189C12) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82931-2-RR

    Affinity and Kinetic Characterization of 82931-2-RR

    Biolayer interferometry (BLl) kinetic assays of 82931-2-RR against Human KHSRP were performed. The affinity constant is 1.42 nM.

KHSRP Recombinant antibody, PBS Only

KHSRP Uni-rAbTM Recombinant Antibody for FC (Intra), IP, Indirect ELISA
Cat No. 82931-2-PBS

产品说明书

CloneNo. 230189C12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra), IP, Indirect ELISA

别名

230189C12, Far upstream element-binding protein 2, FBP2, FUBP2, FUSE-binding protein 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy KHSRP Ready-To-Use IHC Kit. KHSRP primary antibody included.

产品信息

82931-2-PBS targets KHSRP in FC (Intra), IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 FC (Intra), IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 KHSRP fusion protein Ag33890 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 KH-type splicing regulatory protein
别名 230189C12, Far upstream element-binding protein 2, FBP2, FUBP2, FUSE-binding protein 2
计算分子量73 kDa
观测分子量75 kDa
GenBank蛋白编号NM_003685
基因名称 KHSRP
Gene ID (NCBI) 8570
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ92945
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.