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验证数据展示

  • WB analysis using 26426-1-AP (same clone as 26426-1-PBS)

    WB analysis using 26426-1-AP (same clone as 26426-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26426-1-AP (KCNH1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • IP experiment of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    IP experiment of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    IP result of anti-KCNH1 (IP:26426-1-AP, 4ug; Detection:26426-1-AP 1:5000) with rat brain tissue lysate 1720 ug. This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 26426-1-AP (same clone as 26426-1-PBS)

    IP experiment of mouse brain using 26426-1-AP (same clone as 26426-1-PBS)

    IP result of anti-KCNH1 (IP:26426-1-AP, 4ug; Detection:26426-1-AP 1:5000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 26426-1-AP (same clone as 26426-1-PBS)

    IHC staining of mouse brain using 26426-1-AP (same clone as 26426-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 26426-1-AP (KCNH1 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    IHC staining of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 26426-1-AP (KCNH1 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    IHC staining of rat brain using 26426-1-AP (same clone as 26426-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 26426-1-AP (KCNH1 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26426-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

KCNH1 Polyclonal antibody, PBS Only

KCNH1 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 26426-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

别名

EAG, EAG channel 1, EAG1, Ether-a-go-go potassium channel 1, h eag

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

26426-1-PBS targets KCNH1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag16647

Product name: Recombinant human KCNH1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 686-850 aa of BC113709

Sequence: VKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNVLTEHASANHSLVKASVVTVRESPATPVSFQAASTSGVPDHAKLQAPGSECLGPKGGGGDCAKRKSWARFKDACGKSEDWNKVSKAESMETLPERTKASGEATLKKT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 potassium voltage-gated channel, subfamily H (eag-related), member 1
别名 EAG, EAG channel 1, EAG1, Ether-a-go-go potassium channel 1, h eag
计算分子量 989 aa, 111 kDa
观测分子量111 kDa
GenBank蛋白编号BC113709
基因名称 KCNH1
Gene ID (NCBI) 3756
RRIDAB_3742187
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO95259
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Potassium voltage-gated channel subfamily H member 1 (KCNH1, also known as Kv10.1 and EAG) a member of the EAG (ether-à-go-go) family, which is involved in intracellular signaling, cell proliferation, and tumorigenesis (PMID: 35639255). KCNH1 is mainly expressed in the adult central nervous system. It also plays a role in controlling K+ fux that regulates resting membrane potential in excitable and non-excitable cells and is activated at the onset of myoblast differentiation (PMID: 29333676; 27029528; 9738473).

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