验证数据展示
经过测试的应用
| Positive WB detected in | rat brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
83640-5-RR targets KCND3 in WB, ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag22183 Product name: Recombinant human KCND3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 602-636 aa of BC113477 Sequence: PALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | potassium voltage-gated channel, Shal-related subfamily, member 3 |
| 别名 | KV4.3, KSHIVB, KCND3S, KCND3L, 240578F12 |
| 计算分子量 | 655 aa, 73 kDa |
| 观测分子量 | 73 kDa |
| GenBank蛋白编号 | BC113477 |
| 基因名称 | KCND3 |
| Gene ID (NCBI) | 3752 |
| RRID | AB_3671251 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UK17 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KCND3 antibody 83640-5-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
