验证数据展示
产品信息
83640-5-PBS targets KCND3 in WB, Cytometric bead array, Indirect ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag22183 Product name: Recombinant human KCND3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 602-636 aa of BC113477 Sequence: PALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | potassium voltage-gated channel, Shal-related subfamily, member 3 |
| 别名 | 240578F12, KCND3L, KCND3S, KSHIVB, KV4.3 |
| 计算分子量 | 655 aa, 73 kDa |
| GenBank蛋白编号 | BC113477 |
| 基因名称 | KCND3 |
| Gene ID (NCBI) | 3752 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UK17 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
