验证数据展示
经过测试的应用
Positive WB detected in | Daudi cells, Jurkat cells, Raji cells, TT cells, U2OS cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
31900-1-AP targets KCNA6 in WB, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | human |
免疫原 | KCNA6 fusion protein Ag35654 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | potassium voltage-gated channel, shaker-related subfamily, member 6 |
别名 | Protein Phosphatase 1, Regulatory Subunit 96, PPP1R96, Potassium voltage-gated channel subfamily A member 6, Kv1.6, Human Brain Potassium Channel-2 |
计算分子量 | 59 kDa,529aa |
观测分子量 | 65 kDa |
GenBank蛋白编号 | NM_002235.3 |
基因名称 | KCNA6 |
Gene ID (NCBI) | 3742 |
RRID | AB_3670137 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | P17658 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The Shaker-like Kv1 potassium channel family comprises 8 α subunits (Kv1.1-Kv1.8), which are key regulators of neuronal excitability in mammals (PMID: 7842011; 9581771; 22612818). Potassium voltage-gated channel subfamily A member 6 (KCNA6, also known as HBK2, Kv1.6, and PPP1R96) is a multi-pass membrane protein that is mainly expressed in the central and peripheral nervous system (PMID: 12042352; 8872310). The concentration of the Kv1.6 channel in the cell membrane can modulate the kinetic properties of Kv1.6-induced K+ current (PMID: 14575698).
实验方案
Product Specific Protocols | |
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WB protocol for KCNA6 antibody 31900-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |