验证数据展示
发表文章中的应用
WB | See 1 publications below |
IHC | See 1 publications below |
产品信息
17791-1-AP targets Jagged1 in ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | Jagged1 fusion protein Ag11891 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | jagged 1 (Alagille syndrome) |
别名 | AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1 |
计算分子量 | 1218 aa, 134 kDa |
GenBank蛋白编号 | BC098393 |
基因名称 | Jagged1 |
Gene ID (NCBI) | 182 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P78504 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
JAG1, also named as JAGL1, CD339 and Jagged1, is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It may be involved in cell-fate decisions during hematopoiesis. JAG1 seems to be involved in early and late stages of mammalian cardiovascular development. It inhibits myoblast differentiation. JAG1 enhances fibroblast growth factor-induced angiogenesis. JAG1 signalling through notch 1 has also been shown to play a role in hematopoiesis.