Jagged1 Polyclonal antibody

Jagged1 Polyclonal Antibody for ELISA
Cat No. 17791-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

ELISA

AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


产品信息

17791-1-AP targets Jagged1 in ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Jagged1 fusion protein Ag11891 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 jagged 1 (Alagille syndrome)
别名 AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1
计算分子量 1218 aa, 134 kDa
GenBank蛋白编号BC098393
基因名称 Jagged1
Gene ID (NCBI) 182
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP78504
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

JAG1, also named as JAGL1, CD339 and Jagged1, is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It may be involved in cell-fate decisions during hematopoiesis. JAG1 seems to be involved in early and late stages of mammalian cardiovascular development. It inhibits myoblast differentiation. JAG1 enhances fibroblast growth factor-induced angiogenesis. JAG1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

发表文章

SpeciesApplicationTitle
humanWB,IHC

Front Immunol

Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma

Authors - Bo Shi
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