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验证数据展示

  • WB analysis using 87416-2-RR (same clone as 87416-2-PBS)

    WB analysis using 87416-2-RR (same clone as 87416-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87416-2-RR (ITB4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87416-2-PBS in a different storage buffer formulation.

  • Affinity of 87416-2-RR

    Affinity of 87416-2-RR

    Biolayer interferometry (BLl) kinetic assays of 87416-2-RR against Human Integrin beta 4 were performed. The affinity constant is 6.72 nM.

Integrin beta 4 Recombinant monoclonal antibody, PBS Only

Integrin beta 4 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 87416-2-PBS

产品说明书

CloneNo. 252740B3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

ITGB4, CD104, GP150, Integrin beta-4, integrin, beta 4

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy ITGB4 Ready-To-Use IHC Kit. ITGB4 primary antibody included.

产品信息

87416-2-PBS targets Integrin beta 4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Eg10479

Product name: Recombinant human ITB4 protein

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-Twin-Strep-Tag

Domain: 10011436 of

Sequence: \

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, beta 4
别名 ITGB4, CD104, GP150, Integrin beta-4, integrin, beta 4
观测分子量 200 kDa
基因名称 Integrin beta 4
Gene ID (NCBI) 3691
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin beta-4 is predominantly expressed in squamous epithelial cells, endothelial cells, immature thymocytes, Schwann cells, and fibroblasts of the peripheral nervous system (PMID: 28084395). Integrin beta-4 pairs with alpha-6, and the heterodimeric integrin alpha-6/beta-4 is a receptor for laminin. Integrin alpha-6/beta-4 plays a critical structural role in the hemidesmosome of epithelial cells, and also plays a role in the invasive and metastatic phenotype of various cancers.

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