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验证数据展示

  • FC experiment of HT-1080 using 98996-1-RR (same clone as 98996-1-PBS)

    FC experiment of HT-1080 using 98996-1-RR (same clone as 98996-1-PBS)

    1x10^6 HT-1080 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.

  • FC experiment of MCF-7 using 98996-1-RR (same clone as 98996-1-PBS)

    FC experiment of MCF-7 using 98996-1-RR (same clone as 98996-1-PBS)

    1x10^6 MCF-7 cells were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood platelets using 98996-1-RR (same clone as 98996-1-PBS)

    FC experiment of human peripheral blood platelets using 98996-1-RR (same clone as 98996-1-PBS)

    1x10^6 human peripheral blood platelets were surface stained with 0.25 ug Anti-Human Integrin alpha V Rabbit RecAb (98996-1-RR, Clone: 261824A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and CoraLite®647-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98996-1-PBS in a different storage buffer formulation.

Anti-Human Integrin alpha V Rabbit Recombinant Antibody, PBS Only

Integrin alpha V Uni-rAb® Recombinant Antibody for FC
Cat No. 98996-1-PBS

产品说明书

CloneNo. 261824A1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

ITGAV, CD51, Integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98996-1-PBS targets Integrin alpha V in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

unknow

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
别名 ITGAV, CD51, Integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain
基因名称 Integrin alpha V
Gene ID (NCBI) 3685
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP06756
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha V, also known as CD51, is a type I transmembrane glycoprotein composed of an extracellular domain, a transmembrane region and cytoplasmic domain (PMID: 2430295; 1690718). It can form heterodimers with one of the five beta integrin subunits (beta 1, 3, 5, 6, 8) that recognize ligands containing the sequence Arg-Gly-Asp, such as vitronectin, fibronectin, and osteopontin (PMID: 37087799). Integrin alpha V mainly plays a role in extracellular matrix-mediated cell adhesion and migration, differentiation, wound healing, inflammation, tumorigenesis, proliferation, angiogenesis, and metastasis.

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