CoraLite® Plus 488-conjugated Ins1 Monoclonal antibody
Ins1 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
mouse, rat
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1H2C11
验证数据展示
经过测试的应用
| Positive IF detected in | mouse pancreas tissue |
For other applications, we recommend the unconjugated version of this antibody, 67668-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:150-1:600 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
CL488-67668 targets Ins1 in IF applications and shows reactivity with mouse, rat samples.
| Tested Applications | IF-P |
| Cited Applications | IF |
| Tested Reactivity | mouse, rat |
| Cited Reactivity | mouse |
| Immunogen | Ins1 fusion protein Ag29988 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | insulin I |
| Synonyms | Ins 1, Ins1, Ins2 rs1, insulin I |
| Calculated Molecular Weight | 12 kDa |
| GenBank Accession Number | NM_008386 |
| Gene Symbol | Ins1 |
| Gene ID (NCBI) | 16333 |
| RRID | AB_2919515 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P01325 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
insulin I is a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 Ins1 antibody CL488-67668 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
iScience Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP |