验证数据展示
产品信息
87819-1-PBS targets CXCR1/IL-8RA in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | interleukin 8 receptor, alpha |
| 别名 | CD181, C-X-C chemokine receptor type 1, Cxcr1, CXC-R1, CXCR-1 |
| 观测分子量 | 45 kDa |
| GenBank蛋白编号 | BC153097 |
| 基因名称 | Il8ra |
| Gene ID (NCBI) | 227288 |
| RRID | AB_3745769 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q810W6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Mouse Il8ra/Cxcr1 is a Gi-coupled ELR⁺ CXC chemokine receptor expressed mainly on neutrophils, where it contributes to chemotaxis, activation, and inflammatory host defense. Because mice lack a direct IL-8/CXCL8 ortholog, the historical name Il8ra does not fully reflect murine ligand biology, and Cxcr1 is generally considered a more restricted, context-dependent receptor relative to Cxcr2. This distinction is important when using mouse models to study neutrophil trafficking and translational CXCR1 biology.
