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验证数据展示

  • WB analysis using 20729-1-AP (same clone as 20729-1-PBS)

    WB analysis using 20729-1-AP (same clone as 20729-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20729-1-AP (ITPR3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20729-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 20729-1-AP (same clone as 20729-1-PBS)

    IHC staining of mouse colon using 20729-1-AP (same clone as 20729-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 20729-1-AP (ITPR3 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20729-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 20729-1-AP (same clone as 20729-1-PBS)

    IHC staining of mouse cerebellum using 20729-1-AP (same clone as 20729-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 20729-1-AP (ITPR3 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20729-1-PBS in a different storage buffer formulation.

ITPR3 Polyclonal antibody, PBS Only

ITPR3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 20729-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

InsP3R3, IP3R, IP3R 3, IP3R3

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20729-1-PBS targets ITPR3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 inositol 1,4,5-triphosphate receptor, type 3
别名 InsP3R3, IP3R, IP3R 3, IP3R3
计算分子量 304 kDa
观测分子量250-300 kDa
GenBank蛋白编号NM_002224
基因名称 ITPR3
Gene ID (NCBI) 3710
RRIDAB_3669343
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14573
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ITPRs family have three members: ITPR1, ITPR2 and ITPR3. For ITPR3, it is associated with cervical squamous cell carcinoma, glioblastoma, cholangiocarcinoma and other cancers. Inositol 1,4, 5-triphosphate receptor type 3 (ITPR3) was found to be apical-located in bile duct cells, and disruption of lipid raft in the segregated bile duct unit (IBDU) redistributes ITPR3 and impairs Ca2+ waves. (PMID: 35580861, PMID:35852334)

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