验证数据展示
产品信息
18815-1-PBS targets ITLN2 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | intelectin 2 |
| 别名 | Intelectin-2, intelectin 2, HL2, HL 2, Endothelial lectin HL-2 |
| 计算分子量 | 36 kDa |
| 观测分子量 | 36 kDa |
| GenBank蛋白编号 | BC143341 |
| 基因名称 | ITLN2 |
| Gene ID (NCBI) | 142683 |
| RRID | AB_3669302 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8WWU7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ITLN2 also named as UNQ2789 and PRO7179, may play a role in the defense system against pathogens. Intelectins (intestinal lectins) are highly conserved across chordate evolution and have been implicated in various human diseases, including Crohn's disease (CD). The human genome encodes two intelectin genes, intelectin-1 (ITLN1) and intelectin-2 (ITLN2). It is reproted that human ITLN2 is expressed in Paneth cells, where it localizes to secretory granules, and establish that ITLN2 is a highly abundant multimeric protein secreted into the lumen of the small intestine (PMID: 35182405). The calculated molecular weight of ITLN2 is 36 kDa.

