验证数据展示
经过测试的应用
| Positive WB detected in | mouse spleen tissue, mouse colon tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
20231-1-AP targets ITGA6X1A in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | integrin, alpha 6 |
| 别名 | CD49f, Integrin alpha 6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6 |
| 计算分子量 | 127 kDa |
| 观测分子量 | 100 kDa, 150 kDa |
| GenBank蛋白编号 | NM_000210 |
| 基因名称 | Integrin alpha 6 |
| Gene ID (NCBI) | 3655 |
| RRID | AB_10665420 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P23229 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. The antibody is specific to isoform Alpha-6X1A, isoform Alpha-6X2A, isoform Alpha-6X1X2A isoform7 and isoform9 of ITGA6.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ITGA6X1A antibody 20231-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
