验证数据展示
产品信息
19689-1-AP targets INCENP in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | inner centromere protein antigens 135/155kDa |
| 别名 | INCENP, Inner centromere protein |
| 计算分子量 | 105 kDa |
| GenBank蛋白编号 | NM_001040694 |
| 基因名称 | INCENP |
| Gene ID (NCBI) | 3619 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9NQS7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
INCENP belongs to the INCENP family. It’s component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. INCENP probably acts through association with AURKB or AURKC. It seems to bind directly to microtubules. The antibody is to INCENP with Y(822-phopho) and S(831-phopho).
