INCENP Polyclonal antibody

INCENP Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA

Conjugate

Unconjugated

Cat No : 19689-1-AP

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Synonyms

INCENP, Inner centromere protein



产品信息

19689-1-AP targets INCENP in ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name inner centromere protein antigens 135/155kDa
Synonyms INCENP, Inner centromere protein
Calculated Molecular Weight 105 kDa
GenBank Accession NumberNM_001040694
Gene Symbol INCENP
Gene ID (NCBI) 3619
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NQS7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

INCENP belongs to the INCENP family. It’s component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. INCENP probably acts through association with AURKB or AURKC. It seems to bind directly to microtubules. The antibody is to INCENP with Y(822-phopho) and S(831-phopho).