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验证数据展示

  • FC experiment of human PBMCs using 98073-1-RR (same clone as 98073-1-PBS)

    FC experiment of human PBMCs using 98073-1-RR (same clone as 98073-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-1RAP Rabbit RecAb (98073-1-RR, Clone:240756A12) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14 Rabbit Recombinant Antibody (CL647-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98073-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98073-1-RR (same clone as 98073-1-PBS)

    FC experiment of human PBMCs using 98073-1-RR (same clone as 98073-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human IL-1RAP Rabbit RecAb (98073-1-RR, Clone:240756A12) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98073-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98073-1-RR

    Affinity and Kinetic Characterization of 98073-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98073-1-RR against Human IL-1RAP were performed. The affinity constant is 0.572 nM.

    {{ptg:ProductFeaturesInfo}}

Anti-Human IL-1RAP Rabbit Recombinant Antibody, PBS Only

IL-1RAP Uni-rAb® Recombinant Antibody for FC
Cat No. 98073-1-PBS

产品说明书

CloneNo. 240756A12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

IL1RAP, 240756A12, C3orf13, EC:3.2.2.6, IL 1R 3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98073-1-PBS targets IL-1RAP in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg0827

Product name: Recombinant Human IL-1RAP protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 21-359 aa of NM_002182.4

Sequence: SERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKFNYSTAHSAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSPMKLPVHKLYIEYGIQRITCPNVDGYFPSSVKPTITWYMGCYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNAVPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDVTINESISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPRYTVE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 1 receptor accessory protein
别名 IL1RAP, 240756A12, C3orf13, EC:3.2.2.6, IL 1R 3
计算分子量65 kDa
GenBank蛋白编号NM_002182.4
基因名称 IL1RAP
Gene ID (NCBI) 3556
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9NPH3-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-1RAP (Interleukin-1 receptor accessory protein), also known as IL-1RAcP, IL-1R-3, or IL-1R3, is a member of the interleukin-1 receptor family. IL-1RAP is composed of an extracellular region containing three Ig-like C2 type domains, a transmembrane region, and a cytoplasmic region with a TIR (Toll-IL-1-receptor) domain. IL-1RAP functions as a co-receptor for IL-1, IL-33, IL-36. It plays an essential role in the signaling of the IL-1 family cytokines such as IL-1, IL-33, and IL-36, as well as tyrosine kinases FLT3 and c-Kit. IL-1RAP can also exist in a soluble form.