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验证数据展示

  • WB analysis using 84535-2-RR (same clone as 84535-2-PBS)

    WB analysis using 84535-2-RR (same clone as 84535-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84535-2-RR (IL17RA antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84535-2-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP01397-3

    Sandwich ELISA standard curve of MP01397-3

    Sandwich ELISA standard curve of MP01397-3, Human IL17RA Recombinant Matched Antibody Pair - PBS only. 84535-3-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg2317. 84535-2-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL

  • Sample test of MP01397-3

    Sample test of MP01397-3

    The mean IL17RA concentration was determined to be 8.86 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

  • Cytometric bead array standard curve of MP01397-1

    Cytometric bead array standard curve of MP01397-1

    Cytometric bead array standard curve of MP01397-1, IL17RA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84535-1-PBS. Detection antibody: 84535-2-PBS. Standard: Eg2317. Range: 0.625-80 ng/mL.

  • Affinity and Kinetic Characterization of 84535-2-RR

    Affinity and Kinetic Characterization of 84535-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84535-2-RR against Human IL17RA were performed. The affinity constant is below 1 pM.

IL17RA Recombinant antibody, PBS Only (Detector)

IL17RA Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 84535-2-PBS

产品说明书

CloneNo. 241891E11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

别名

CD217, IL 17 receptor A, hIL 17R, CDw217, CANDF5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84535-2-PBS targets IL17RA as part of a matched antibody pair:

MP01397-1: 84535-1-PBS capture and 84535-2-PBS detection (validated in Cytometric bead array)

MP01397-3: 84535-3-PBS capture and 84535-2-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 17 receptor A
别名 CD217, IL 17 receptor A, hIL 17R, CDw217, CANDF5
计算分子量 866 aa, 96 kDa
观测分子量100-130 kDa
GenBank蛋白编号BC011624
基因名称 IL17RA
Gene ID (NCBI) 23765
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ96F46
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-17 receptor A (IL17A) is a major effector cytokine of the innate and adaptive immune system and is involved in antimicrobial host defense and maintenance of tissue integrity. It has been shown that IL-17A is involved in the pathogenesis of asthma and allergy and regulates local immune and inflammatory processes in bone tissue and is involved in the onset and progression of osteoporosis. In addition to this, due to polymorphisms in the IL17RA gene, it leads to the development of Fanconi anemia.