CoraLite® Plus 647-conjugated IL-22RA2 Polyclonal antibody
IL-22RA2 Polyclonal Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
FC (Intra)
Conjugate
CoraLite® Plus 647 Fluorescent Dye
验证数据展示
经过测试的应用
Positive FC detected in | HeLa cells |
For other applications, we recommend the unconjugated version of this antibody, 22861-1-AP
推荐稀释比
Application | Dilution |
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Flow Cytometry (FC) | FC : 0.20 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of CL647-22861 is IL-22RA2 Fusion Protein expressed in E. coli.
Tested Applications | FC (Intra) |
Tested Reactivity | human |
Immunogen | IL-22RA2 fusion protein Ag18854 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | interleukin 22 receptor, alpha 2 |
Synonyms | CRF2 10, CRF2 S1, CRF2X, IL 22 receptor subunit alpha 2, IL 22BP, IL 22R alpha 2, IL 22RA2, IL22BP, IL22RA2, Interleukin 22 binding protein, ZcytoR16 |
Calculated Molecular Weight | 263 aa, 31 kDa |
Observed Molecular Weight | 27 kDa |
GenBank Accession Number | BC125167 |
Gene Symbol | IL22RA2 |
Gene ID (NCBI) | 116379 |
Conjugate | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q969J5 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Interleukin-22 receptor subunit alpha-2 (IL22RA2, also known as CRF2-10) is a soluble member of the type II cytokine receptor family. Through binding to IL22, IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. It has been described that human IL22RA2 gene encodes three alternatively spliced isoforms called CRF2-10L, CRF2-10, and CRF2-10s, with molecular weights of 31 kDa, 27 kDa, and 15 kDa, respectively.
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 647 IL-22RA2 antibody CL647-22861 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |