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验证数据展示

  • FC experiment of Transfected HEK-293T using 98846-3-RR (same clone as 98846-3-PBS)

    FC experiment of Transfected HEK-293T using 98846-3-RR (same clone as 98846-3-PBS)

    1x10^6 HEK-293T cells (left) or IL-18-transfected HEK-293T cells(right) were intracellularly stained with 0.25 ug Anti-Mouse IL-18 Rabbit RecAb (98846-3-RR, Clone: 252154A6) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed and permeabilized with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019). This data was developed using the same antibody clone with 98846-3-PBS in a different storage buffer formulation.

  • FC experiment of Transfected HEK-293T using 98846-3-RR (same clone as 98846-3-PBS)

    FC experiment of Transfected HEK-293T using 98846-3-RR (same clone as 98846-3-PBS)

    1x10^6 HEK-293T cells (left) or IL-18-transfected HEK-293T cells(right) were intracellularly stained with 0.25 ug Anti-Mouse IL-18 Rabbit RecAb (98846-3-RR, Clone: 252154A6) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed and permeabilized with Intracellular Flow Cytometry Fixation & Permeabilization Buffer Kit (PF00019). This data was developed using the same antibody clone with 98846-3-PBS in a different storage buffer formulation.

Anti-Mouse IL-18 Rabbit Recombinant Antibody, PBS Only

IL-18 Uni-rAb® Recombinant Antibody for FC (Intra)
Cat No. 98846-3-PBS

产品说明书

CloneNo. 252154A6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC (Intra)

别名

IFN-gamma-inducing factor, Igif, IL-1 gamma, Il18, Interferon gamma-inducing factor

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98846-3-PBS targets IL-18 in FC (Intra) applications and shows reactivity with mouse samples.

经测试应用 FC (Intra) Application Description
经测试反应性 mouse
免疫原

CatNo: Eg4455

Product name: Recombinant Mouse IL-18 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-N-rFc

Tag: N-rFc

Domain: 1-192 aa of NM_008360.1

Sequence: MAAMSEDSCVNFKEMMFIDNTLYFIPEENGDLESDNFGRLHCTTAVIRNINDQVLFVDKRQPVFEDMTDIDQSASEPQTRLIIYMYKDSEVRGLAVTLSVKDSKMSTLSCKNKIISFEEMDPPENIDDIQSDLIFFQKRVPGHNKMEFESSLYEGHFLACQKEDDAFKLILKKKDENGDKSVMFTLTNLHQS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 18
别名 IFN-gamma-inducing factor, Igif, IL-1 gamma, Il18, Interferon gamma-inducing factor
计算分子量22 kDa
GenBank蛋白编号NM_008360.1
基因名称 Il18
Gene ID (NCBI) 16173
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP70380
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-18 is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL-18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL-18 is synthesized as a 22 kDa precursor and then cleaved into a biologically activate 18 kDa form.

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