IL-15RA Monoclonal antibody, PBS Only

IL-15RA Monoclonal Antibody for WB, Indirect ELISA
Cat No. 60138-1-PBS

产品说明书

CloneNo. 5E3E1

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

IL15RA, 5E3E1, CD215, IL 15 receptor subunit alpha, IL 15R alpha

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

60138-1-PBS targets IL-15RA in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 IL-15RA fusion protein Ag10200 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 15 receptor, alpha
别名 IL15RA, 5E3E1, CD215, IL 15 receptor subunit alpha, IL 15R alpha
计算分子量 231 aa, 24 kDa
观测分子量 55 kDa
GenBank蛋白编号BC107777
基因名称 IL-15RA
Gene ID (NCBI) 3601
RRIDAB_2881352
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ13261
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-15 (IL-15) is a pleiotropic cytokine that plays an important role in both innate and adaptive immunity. IL-15 is mainly produced by activated monocytes, macrophages and dendritic cells, and is structurally similar to IL-2 (PMID: 8178155; 12401478). These two cytokines share the same IL-2/15Rβ and common γ-chain receptor subunits. In addition, IL-2 and IL-15 have their own private α-chain receptor subunit, IL-2Rα and IL-15Rα, respectively (PMID: 7641685). The IL-15Rα chain is expressed by many cell types including monocytes, DCs, NK, T cells and fibroblasts. Several isoforms of IL-15Rα exist and are generated either by alternative splicing or by proteolytic cleavage (PMID: 10480910; 15265897). The calculated molecular weight of full-length IL-15Rα is 28 kDa, IL-15Rα can be glycosylated, and larger apparent molecular weights of 55-65 kDa have been reported by some researches (PMID: 10480910; 15976182; 15671076; 17912462).

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