验证数据展示
产品信息
16759-1-PBS targets IGDCC3 in IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IP, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag10276 Product name: Recombinant human IGDCC3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 37-401 aa of BC067107 Sequence: GHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | immunoglobulin superfamily, DCC subclass, member 3 |
| 别名 | |
| 计算分子量 | 814 aa, 87 kDa |
| 观测分子量 | 87 kDa |
| GenBank蛋白编号 | BC067107 |
| 基因名称 | IGDCC3 |
| Gene ID (NCBI) | 9543 |
| RRID | AB_3669255 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8IVU1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IGDCC3, also known as PUNC, is a transmembrane protein that belongs to the immunoglobulin (Ig) superfamily (PMID: 9507132). IGDCC3 contains 4 C2-type Ig-like domains and 2 fibronectin type III repeats. It is highly expressed in the developing embryo in nervous system, limbs, and inner ear (PMID: 9922388; 9507132). IGDCC3 may be involved in the cerebellar control of motor coordination (PMID: 11486040). It has also been associated with tumorigenic mechanism and prognosis of cholangiocarcinoma (PMID: 36979826).
