验证数据展示
经过测试的应用
| Positive IP detected in | human placenta tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
16759-1-AP targets IGDCC3 in IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IP, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | IGDCC3 fusion protein Ag10276 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | immunoglobulin superfamily, DCC subclass, member 3 |
| 别名 | HsT18880, IGDCC3, PUNC |
| 计算分子量 | 814 aa, 87 kDa |
| 观测分子量 | 87 kDa |
| GenBank蛋白编号 | BC067107 |
| 基因名称 | IGDCC3 |
| Gene ID (NCBI) | 9543 |
| RRID | AB_3669255 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8IVU1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IGDCC3, also known as PUNC, is a transmembrane protein that belongs to the immunoglobulin (Ig) superfamily (PMID: 9507132). IGDCC3 contains 4 C2-type Ig-like domains and 2 fibronectin type III repeats. It is highly expressed in the developing embryo in nervous system, limbs, and inner ear (PMID: 9922388; 9507132). IGDCC3 may be involved in the cerebellar control of motor coordination (PMID: 11486040). It has also been associated with tumorigenic mechanism and prognosis of cholangiocarcinoma (PMID: 36979826).
实验方案
| Product Specific Protocols | |
|---|---|
| IP protocol for IGDCC3 antibody 16759-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |