验证数据展示
经过测试的应用
| Positive FC detected in | U-937 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
PE-FcA98067 targets IFNAR1 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | human |
| 免疫原 | IFNAR1 fusion protein Eg0156 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | interferon (alpha, beta and omega) receptor 1 |
| 别名 | 230549B1, AVP, CRF2 1, CRF2-1, Cytokine receptor class-II member 1 |
| 计算分子量 | 557 aa, 64 kDa |
| GenBank蛋白编号 | BC021825 |
| 基因名称 | IFNAR1 |
| Gene ID (NCBI) | 3454 |
| 偶联类型 | PE Fluorescent Dye |
| 最大激发/发射波长 | 496 nm, 565 nm / 578 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3 |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for PE IFNAR1 antibody PE-FcA98067 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |