ICMT Polyclonal antibody
ICMT Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
18983-1-AP targets ICMT in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Tested Reactivity | human, mouse, rat |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | isoprenylcysteine carboxyl methyltransferase |
| Synonyms | HSTE14, ICMT, MST098, MSTP098, PCCMT, PCMT, PPMT |
| Calculated Molecular Weight | 32 kDa |
| GenBank Accession Number | NM_012405 |
| Gene Symbol | ICMT |
| Gene ID (NCBI) | 23463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O60725 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ICMT, also named as PCCMT and PPMT, belongs to the isoprenylcysteine O-methyltransferase family. ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. It localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. It is ubiquitously expressed. It expressed at higher levels in the cerebellum and putamen than in other brain regions and abundant expression seen in the Purkinje cells and pontine neurons.