Recombinant Human C-Reactive Protein/CRP protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human C-Reactive Protein protein Gln19-Pro224 (Accession# P02741-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 1401 |
| 蛋白编号 | P02741-1 |
| 预测分子量 | 49.3 kDa |
| SDS-PAGE | 47-53 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.
参考文献:
1. Rizo-Téllez, Salma A et al. Frontiers in immunology vol. 14 1237729. 26 Jul. 2023. 2. Black, Steven et al. The Journal of biological chemistry vol. 279,47 (2004): 48487-90. 3. Zhou, Hai-Hong et al. Frontiers in immunology vol. 15 1425168. 14 Jun. 2024.
