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验证数据展示

  • WB analysis of human plasma using 66229-1-Ig (same clone as 66229-1-PBS)

    WB analysis of human plasma using 66229-1-Ig (same clone as 66229-1-PBS)

    0.5 μl human plasma was subjected to SDS PAGE followed by western blot with 66229-1-Ig (HP Antibody) at dilution of 1:40000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66229-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66229-1-Ig (same clone as 66229-1-PBS)

    IHC staining of human liver cancer using 66229-1-Ig (same clone as 66229-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66229-1-Ig (Haptoglobin antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66229-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with HP antibody included
  • IHC staining of human liver cancer using 66229-1-Ig (same clone as 66229-1-PBS)

    IHC staining of human liver cancer using 66229-1-Ig (same clone as 66229-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66229-1-Ig (Haptoglobin antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66229-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with HP antibody included

Haptoglobin Monoclonal antibody, PBS Only

Haptoglobin Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66229-1-PBS

产品说明书

CloneNo. 3B4B9

宿主/亚型

Mouse / IgG2b

种属反应性

human, pig

应用

WB, IHC, Indirect ELISA

别名

BP, HAPT, haptoglobin, HP, HP2 ALPHA 2, HPA1S, Zonulin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy HP Ready-To-Use IHC Kit. HP primary antibody included.

产品信息

66229-1-PBS targets Haptoglobin in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, pig
免疫原 Haptoglobin fusion protein Ag9927 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 haptoglobin
别名 BP, HAPT, haptoglobin, HP, HP2 ALPHA 2, HPA1S, Zonulin
计算分子量281aa,31 kDa; 228aa,25 kDa
观测分子量 42 kDa
GenBank蛋白编号BC058031
基因名称 HP
Gene ID (NCBI) 3240
RRIDAB_2881620
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP00738
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HP(Haptoglobin) is also named as zonulin and belongs to the peptidase S1 family. HP, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha(16 kDa and 9 kDa) and 2 beta(40 kDa) polypeptides that are covalently associated by disulfide bonds. In most species, apart from ruminants, Hp has a molecular mass of 100 kDa, consisting of two subunits of 40 kDa and two subunits of 9 kDa, although in a few species, such as man, genetic variant of Hp forms polymers of higher mass(PMID:2361363). Recent studies of haptoglobin show that certain oligosaccharide structures predominate in different diseases. For example, a highly-fucosylated structure is found in breast cancer and ovarian cancer, highly-sialylated structures in Crohn’s disease and highly branched structures in alcoholic liver disease and fucosylated haptoglobin is a good serum marker for pancreatic cancer.(PMID:16385567).