CoraLite® Plus 488-conjugated HVCN1 Monoclonal antibody
HVCN1 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1E4C4
验证数据展示
经过测试的应用
| Positive IF detected in | human tonsillitis tissue |
For other applications, we recommend the unconjugated version of this antibody, 66449-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-66449 targets HVCN1 in IF applications and shows reactivity with human samples.
| Tested Applications | IF-P |
| Tested Reactivity | human |
| Immunogen | HVCN1 fusion protein Ag5350 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | hydrogen voltage-gated channel 1 |
| Synonyms | HV1, HVCN1, VSOP |
| Calculated Molecular Weight | 273 aa, 32 kDa |
| Observed Molecular Weight | 28-35 kDa, 40 kDa, 60 kDa |
| GenBank Accession Number | BC032672 |
| Gene Symbol | HVCN1 |
| Gene ID (NCBI) | 84329 |
| RRID | AB_2919328 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q96D96 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HVCN1, also named as VSOP and HV1, Belongs to the hydrogen channel family. HVCN1 mediates the voltage-dependent proton permeability of excitable membranes. It forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, HVCN1 is accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. HVCN1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm. HVCN1 has four isoforms with MW 28-32 kDa or 40 kDa (modification). It has a dimer form with MW 60 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 HVCN1 antibody CL488-66449 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |