CoraLite® Plus 488-conjugated HBS1L Monoclonal antibody
HBS1L Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1A10C4
验证数据展示
经过测试的应用
| Positive IF detected in | U2OS cells |
For other applications, we recommend the unconjugated version of this antibody, 68146-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-68146 targets HBS1L in IF applications and shows reactivity with Human samples.
| Tested Applications | IF/ICC |
| Tested Reactivity | Human |
| Immunogen | HBS1L fusion protein Ag0388 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | HBS1-like (S. cerevisiae) |
| Synonyms | DKFZp686L13262, EF 1a, ERFS, HBS1, HBS1 like (S. cerevisiae), HBS1 like protein, HBS1L, HSPC276, KIAA1038 |
| Calculated Molecular Weight | 75 kDa |
| Observed Molecular Weight | 75 kDa |
| GenBank Accession Number | BC001465 |
| Gene Symbol | HBS1L |
| Gene ID (NCBI) | 10767 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9Y450 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HBS1L (HBS1-like), also known as EF-1a or ERFS, is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and beta-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.This antibody specifically recognizes the 75kd human HBS1L protein.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 HBS1L antibody CL488-68146 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |