验证数据展示
产品信息
33317-1-PBS targets HABP4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag39922 Product name: Recombinant human HABP4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 280-413 aa of NM_014282.3 Sequence: LEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | hyaluronan binding protein 4 |
| 别名 | Hyaluronan-binding protein 4, IHABP4, IHABP-4, Intracellular hyaluronan-binding protein 4, Ki-1/57 intracellular antigen |
| 计算分子量 | 46kDa，413aa |
| 观测分子量 | 57 kDa |
| GenBank蛋白编号 | NM_014282.3 |
| 基因名称 | HABP4 |
| Gene ID (NCBI) | 22927 |
| RRID | AB_3742938 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q5JVS0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HABP4 (hyaluronic acid binding protein 4) is an intracellular regulatory protein, with a molecular weight of about 57 kDa (PMID: 33245729), which is rich in positively charged amino acids and can bind with negatively charged macromolecules such as RNA and hyaluronic acid. It has SUMO binding activity, participates in PML tissue, negatively regulates DNA binding activity, and positively regulates gene expression. In addition, HABP4 has a complex interaction network in cells, and has undergone a variety of post-translational modifications, including serine/threonine phosphorylation, arginine methylation and SUMO.
