• Featured Product
  • KD/KO验证

GSDMB Polyclonal antibody

GSDMB Polyclonal Antibody for WB, IHC, ELISA
Cat No. 12885-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, ELISA and More (1)

Gasdermin-like protein, Gasdermin-B, N-terminal, Gasdermin-B, C-terminal, Gasdermin-B, Gasdermin like protein

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inA431 cells
Positive IHC detected inhuman liver cancer tissue, human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12885-1-AP targets GSDMB in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human
文献引用反应性human
免疫原

CatNo: Ag3895

Product name: Recombinant human GSDMB protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-385 aa of BC025682

Sequence: MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISRELHMEDSDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gasdermin B
别名 Gasdermin-like protein, Gasdermin-B, N-terminal, Gasdermin-B, C-terminal, Gasdermin-B, Gasdermin like protein
计算分子量 411 aa, 47 kDa
观测分子量 47 kDa
GenBank蛋白编号BC025682
基因名称 GSDMB
Gene ID (NCBI) 55876
RRIDAB_2114762
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TAX9
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

实验方案

Product Specific Protocols
WB protocol for GSDMB antibody 12885-1-APDownload protocol
IHC protocol for GSDMB antibody 12885-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
Human

Am J Respir Cell Mol Biol

Glutaminolysis Epigenetically Regulates Anti-Apoptotic Gene Expression in IPF Fibroblasts.

Authors - Le Bai
humanIHC,WB

Front Immunol

Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma

Authors - Liangmin Fu
  • KD Validated
humanWB, IHC

Int J Biol Sci

USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.

Authors - Haiqing He
humanIHC

Front Oncol

Novel Pyroptosis-Related Gene Signatures Identified as the Prognostic Biomarkers for Bladder Carcinoma.

Authors - Jia You

J Biol Chem

Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.

Authors - Karen Bernard
humanWB

J Allergy Clin Immunol

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

Authors - Ronald A Panganiban
Loading...