mGluR2 Polyclonal antibody

mGluR2 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 19956-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

GLUR2, GPRC1B, GRM2, mGlu2, mGluR2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman brain tissue, HeLa cells, rat brain tissue
Positive IHC detected inmouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

19956-1-AP targets mGluR2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse, rat
文献引用反应性human, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutamate receptor, metabotropic 2
别名 GLUR2, GPRC1B, GRM2, mGlu2, mGluR2
计算分子量 96 kDa
观测分子量 96 kDa, 120 kDa
GenBank蛋白编号NM_000839
基因名称 mGluR2
Gene ID (NCBI) 2912
RRIDAB_10638447
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14416
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GRM2, also named as GPRC1B and MGLUR2, belongs to the G-protein coupled receptor 3 family. GRM2 is a receptor for glutamate. The activity of GRM2 is mediated by a G-protein that inhibits adenylate cyclase activity. It may mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

实验方案

Product Specific Protocols
WB protocol for mGluR2 antibody 19956-1-APDownload protocol
IHC protocol for mGluR2 antibody 19956-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Mol Cancer Res

Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells.

Authors - Javierre Biola M BM
ratWB,IHC

Auton Neurosci

Expression of group II metabotropic glutamate receptors in rat superior cervical ganglion

Authors - Xixi Wei
ratWB,IHC

Neurochem Int

Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-α and IL-1β

Authors - Wen-Tao Wang
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