验证数据展示
产品信息
85907-4-PBS targets GRK6 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | GRK6 fusion protein Ag1992 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | G protein-coupled receptor kinase 6 |
| 别名 | EC:2.7.11.16, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6 |
| 计算分子量 | 66 kDa |
| 观测分子量 | 65 kDa |
| GenBank蛋白编号 | BC017272 |
| 基因名称 | GRK6 |
| Gene ID (NCBI) | 2870 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P43250 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GRK6 (G Protein-Coupled Receptor Kinase 6) is a member of the G protein-coupled receptor kinase (GRK) family, which plays a crucial role in regulating the activity of G protein-coupled receptors (GPCRs). GRK6 specifically phosphorylates the activated forms of GPCRs, initiating their desensitization, internalization, and signaling events that lead to receptor deactivation. This process is essential for maintaining proper cellular responses to extracellular signals.