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验证数据展示

  • IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

    IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25999-1-AP (GPR87 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25999-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

    IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25999-1-AP (GPR87 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25999-1-PBS in a different storage buffer formulation.

GPR87 Polyclonal antibody, PBS Only

GPR87 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 25999-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

25999-1-PBS targets GPR87 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag23214

Product name: Recombinant human GPR87 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-47 aa of BC132888

Sequence: MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 87
别名
GenBank蛋白编号BC132888
基因名称 GPR87
Gene ID (NCBI) 53836
RRIDAB_3085833
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BY21
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

G Protein-Coupled Receptor 87 (GPR87) is a GPCR, and it has been demonstrated to regulate the progression of several tumors (PMID:18183596). Studied reported that GPR87 promotes PDA (Pancreatic ductal adenocarcinoma) proliferation, angiogenesis, gemcitabine resistance, and tumorigenicity through activating the nuclear factor-kB (NF-kB) pathway (PMID:32405536). GPR87 is an independent prognostic factor for bladder cancer intravesical recurrence; it promotes bladder cancer cell proliferation and inhibits apoptosis. In addition, GPR87 was deorphanized and shown to be a lysophosphatidic acid (LPA) receptor (PMID:23752273).

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