验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, fetal human brain tissue, rat brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
87758-1-RR targets GPR83 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | G protein-coupled receptor 83 |
| 别名 | G protein coupled receptor 72, G protein coupled receptor 83, GIR, GPR72, G-protein coupled receptor 72 |
| 计算分子量 | 423 aa, 48 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC067473 |
| 基因名称 | GPR83 |
| Gene ID (NCBI) | 10888 |
| RRID | AB_3745735 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NYM4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GPR83 is a class A GPCR expressed in both hypothalamic neuronal circuits and regulatory T cells, linking it to energy balance, stress responses, and immune regulation. Although its endogenous ligands and signaling mechanisms remain incompletely defined, GPR83 is increasingly recognized as a context-dependent modulator of Treg-associated immune tolerance and neuroendocrine control of metabolism. These features position GPR83 as an emerging target in metabolic and immunoregulatory research.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for GPR83 antibody 87758-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
