验证数据展示
产品信息
87758-1-PBS targets GPR83 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | G protein-coupled receptor 83 |
| 别名 | G protein coupled receptor 72, G protein coupled receptor 83, GIR, GPR72, G-protein coupled receptor 72 |
| 计算分子量 | 423 aa, 48 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC067473 |
| 基因名称 | GPR83 |
| Gene ID (NCBI) | 10888 |
| RRID | AB_3745735 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NYM4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GPR83 is a class A GPCR expressed in both hypothalamic neuronal circuits and regulatory T cells, linking it to energy balance, stress responses, and immune regulation. Although its endogenous ligands and signaling mechanisms remain incompletely defined, GPR83 is increasingly recognized as a context-dependent modulator of Treg-associated immune tolerance and neuroendocrine control of metabolism. These features position GPR83 as an emerging target in metabolic and immunoregulatory research.

