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验证数据展示

  • IHC staining of human kidney using 28096-1-AP (same clone as 28096-1-PBS)

    IHC staining of human kidney using 28096-1-AP (same clone as 28096-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 28096-1-AP (GPR141 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28096-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 28096-1-AP (same clone as 28096-1-PBS)

    IHC staining of human kidney using 28096-1-AP (same clone as 28096-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 28096-1-AP (GPR141 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28096-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28096-1-AP (same clone as 28096-1-PBS)

    IHC staining of mouse brain using 28096-1-AP (same clone as 28096-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28096-1-AP (GPR141 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28096-1-PBS in a different storage buffer formulation.

GPR141 Polyclonal antibody, PBS Only

GPR141 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 28096-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

28096-1-PBS targets GPR141 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag23129

Product name: Recombinant human GPR141 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 246-305 aa of BC120951

Sequence: IYYLNVVTHSNACNSKVAFYNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGLWNCVLCR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 141
别名
计算分子量 305 aa, 35 kDa
GenBank蛋白编号BC120951
基因名称 GPR141
Gene ID (NCBI) 353345
RRIDAB_3086028
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ7Z602
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR141 (G-protein-coupled receptor 141) is a class A orphan receptor molecule of the rhodopsin family. Increased GPR141 expression enhances the migratory behavior of breast cancer, driving oncogenic pathways both in vitro and in vivo through activation of epithelial to mesenchymal transition (EMT), oncogenic mediators, and regulation of p-mTOR/p53 signaling (PMID: 37204251).

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