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验证数据展示

  • IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    IHC staining of mouse kidney using 17774-1-AP (same clone as 17774-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17774-1-AP (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17774-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

GPR126 Polyclonal antibody, PBS Only

GPR126 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 17774-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

17774-1-PBS targets GPR126 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag12195

Product name: Recombinant human GPR126 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 45-399 aa of BC075798

Sequence: LSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYSNASFTQLLSFGKAKSGYFLSISDSQCLLNNALPVKEKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEIVSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSCGSYLIPLPAAELASCADLGTLCQDGIIYRISVVIQNILRHPEV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 126
别名
计算分子量 1222 aa, 137 kDa
GenBank蛋白编号BC075798
基因名称 GPR126
Gene ID (NCBI) 57211
RRIDAB_2878439
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86SQ4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.

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